Our mission is to give clinicians the ability to measure fracture healing with confidence. We develop sensors on implanted medical devices to quantitatively track fracture healing and measure local infection biomarkers.

Musculoskeletal diseases affect over half the US population aged 18+, and nearly three quarters of the 65+ population.¹ On average people have two fractures during their lifetime. These fractures are often surgically treated; many people also undergo procedures for other orthopaedic conditions. Following orthopedic surgery patients are scheduled to follow-up with their medical team to monitor progress and manage treatment. Plain radiography is commonly used to evaluate anatomy and detect pathologies; however, interpretation of fracture healing is subjective and imprecise. Quantitative assessments would allow physicians to intervene to avoid complication with slowly healing fractures and have more confidence with normally healing patients.

Learn more about our technologies.

 

Two recent reviews on fracture non-union highlight the importance of this concern:

“Today, the remaining bottleneck in evidenced-based fracture care is the virtual absence of clinical tools that allow for direct, quantitative assessment of the fracture healing state.” ²

“The answer to whether we need a better assessment of fracture healing is an unqualified yes.” ³


Our Team

Our team has experts in orthopedic implants, orthopedic surgery, sensing/imaging, mechanical testing, and business development. Together we have years of experience working together on three multiyear NIH grants and a DoD grant. Our interdisciplinary team will develop innovative techniques with potentially transformative orthopedic applications.

Jeffrey N. Anker, CEO

Founder, CEO, and co-inventor Jeffrey Anker, Ph.D. is a Wallace R. Roy Distinguished Professor of Chemistry and BioEngineering at Clemson University and has expertise in imaging and sensor development.

John DesJardins, CTO

Founder, CTO, and co-inventor Dr. DesJardins, PhD, is the Robert B. and Susan B. Hambright Leadership Professor in Bioengineering at Clemson University.

Caleb Behrend, CMO

Co-founder co-inventor, and CMO Caleb Behrend, MD/MS, is an attending orthopedic spine surgeon.


Advisory Board

Dave Eldridge

Tri-county Entrepreneurial Corporation, NSF ICORPS Business Mentor

John Bachman

Retired DG for J&J Medical Devices for Europe

Randy Moore

Retired, President & Plant Manager for Mitsubishi Fibers in Greenville, SC

Tom Borg

Retired Chair of Regenerative Medicine Department at MUSC

References

  1. Weinstein SI, Yelin EH. BMUS: The Burden of Musculoskeletal Diseases in the United States, 4th Edition. Rosemont, IL: United States Bone and Joint Initiative; 2018.

  2. M. Bottlang and P. Augat, Injury, 45S, 2014.

  3. Delayed union and nonunions: Epidemiology, clinical issues, and financial aspects, D.J. Hak et al. Injury 45S (2014) S3-7.

  4. MarketResearch.com. The Global Market for Medical Devices, 8th Edition. Kalorama Information; 2017 Oct. Report. No.: 11198459.

  5. MarketResearch.com. Global Orthopedic Device Market (Hip, Knee, Spine, Extremities and Trauma Devices). Kalorama Information; 2015 Feb. Report No.: 8757580.